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Thursday, September 5, 2013
HIV Vaccine Reported To Be Successful In Trials.By. Canadian University
HIV vaccine reported to be successful in trials by
Canadian university
Researchers at the University of Western Ontario
recently completed Phase 1 human trials of a new
preventative HIV vaccine, and the results give hope
that they may be on track towards a commercially
available vaccine that will protect against HIV.
The vaccine, called SAV001-H, was developed by Dr.
Chil-Yong Kang and his team at Western University's
Schulich School of Medicine & Dentistry. So far,
SAV001-H is unique in being the only preventative
vaccine to use a genetically-modified version of the
whole virus (similar to vaccines for polio, influenza
and rabies, to name a few).
"We infect the cells with a genetically modified
HIV-1," Kang said in an interview with Ontario
Business Report. "The infected cells produce lots of
virus, which we collect, purify and inactivate so that
the vaccine won’t cause AIDS in recipients, but will
trigger immune responses."
This will hopefully make the vaccine not only
effective, but easy and cheap to produce.
Now, Phase 1 trials (which started in March of 2012)
are specifically to test if the vaccine is safe, and to
identify any side effects (if any). It's not until Phases
2 and 3 that the actual effectiveness of the vaccine is
truly put to the test. However, it seems that SAV001-
H passed its Phase 1 trials with flying colours, since
no adverse effects were reported in any of the
patients that participated in the study.
[ More Geekquinox: Mammals could harbour over
300,000 unknown viruses ]
With this success, it now opens the doors for Kang
and his team to continue on with Phase 2 trials,
where they'll test the vaccine's ability to produce an
immune response and its overall effectiveness.
Dr. Kang goes into details about the vaccine and the trials on this video..
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