Friday, September 13, 2013
Heart attack technique 'could save lives'
A new, relatively simple way of treating heart
attacks could save thousands of lives,
according to specialists at a Clydebank
hospital.
It involves clearing all narrowed arteries when
someone is admitted with a heart attack, rather than
just the one which is completely blocked.
A trial, involving the Golden Jubilee National Hospital,
was so successful that the research was stopped
early.
Jubilee heart specialist Prof Colin Berry said the
results were "striking".
Fatty deposits
Another cardiologist, Prof Keith Oldroyd, said: "At the
moment when patients come in with a heart attack
they have an emergency angiogram and we usually
only treat the artery that has caused the heart
attack.
"Many of these patients have additional narrowings
in other arteries. We're treating all the narrowed
arteries at the same time to see if that confers
additional benefit."
Every year 25,000 people in the UK have the kind of
heart attack which is treated with an angioplasty.
This involves inserting a stent, or thin tube, to open
an artery and restore the blood flow.
Arteries become narrowed by fatty deposits, so
although a blood clot may have only blocked one
artery, other narrowed arteries are common.
Current UK recommendations advise specialists only
to treat the artery which is completely blocked.
"Most cardiologists thought it wasn't safe to treat a
second or third artery at the same time as the first
artery," Prof Oldroyd said.
"Sometimes the patients would be brought back
several weeks later or sometimes only medication
would be used. The results of this trial suggest that
this recommendation should be revisited."
Reducing costs
The trial involved 465 patients in five specialist heart
centres around the UK. In addition to the Golden
Jubilee, they were the London Chest Hospital,
Morriston Hospital in Swansea, Freeman Hospital in
Newcastle, and Norfolk and Norwich University
Hospital.
Half of the trial participants had all their arteries
cleared, the rest were treated in the conventional
way.
Prof Keith Oldroyd said most patients had narrowings
in more than one artery
The researchers found that the new technique
reduced the combined risk of dying, having another
heart attack or being left with angina by two-thirds -
such a significant finding that the trial was stopped
early.
It also only added an average of 20 minutes to each
treatment.
The results have been published in the New England
Journal of Medicine and were presented at an
international conference in Amsterdam earlier this
month.
Prof Colin Berry, heart specialist at the Golden Jubilee
and the University of Glasgow, said: "They were some
of the most striking results for a treatment that I
have ever seen. The results of this trial really
challenge clinical practice."
Heart specialists are now keen that even larger
studies get under way as quickly as possible.
In the past, it has taken a decade or more for the
latest evidence to be adopted into frontline medical
care.
Prof Berry added: "It's appealing because it's a form
of usual care that can be readily adopted across the
UK.
"On the other hand there are logistical considerations
and cost considerations. However, we would argue
that reducing the likelihood of further cardiac events,
potentially reducing the heart failure admissions to
hospital, is going to reduce costs overall and this
should be implemented as soon as possible."
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